Mibelas 24 Fe is a combination hormone drug which is used for birth control. The drug contains 2 female hormones, ethinyl estradiol and norethindrone.
Contents:
Indications for use
- Hormonal contraception.
Mechanism of action
The active substances of the drug, ethinyl estradiol and norethindrone, prevent the full development of a woman’s egg during your menstrual cycle. It also makes vaginal fluid thicker to help prevent fertilization and changes the lining of the womb, which prevents the attachment of a fertilized egg.
Dosage and mode of application
Mibelas 24 Fe pack includes 28 tablets:
- 24 white chewable tablets (active), each containing 1 mg norethindrone and 20 mcg ethinyl estradiol;
- 4 brown mottled tablets (inactive), each containing 75 mg ferrous fumarate, which do not provide any therapeutic effect and serve as reminders.
Start taking the drug on the Day 1 of your menstrual period or on the first Sunday following the onset of your menstrual period. You may need to use an additional barrier contraceptive method when you are using the first pack of the drug. Consult your healthcare provider for more details.
You should take 1 tablet per day, for 28 days in a row, at the same time. Once you have taken the last inert tablets from the blister, start a new pack the next day. Your period should begin in the non-hormone period. Try not to miss doses because you may become pregnant.
Overdose
Strictly follow the dosing regimen. An overdose of ethinyl estradiol and norethindrone can cause nausea, vomiting, difficulty breathing, vaginal bleeding. If you have any disturbing symptoms after taking an excessive dose of the drug, contact your doctor immediately.
Side effects
Mibelas 24 Fe causes side effects in rare cases. They may include:
- hypertension;
- abnormal vaginal bleeding
- dark urine;
- changes in mood;
- breast pain/discomfort,enlargement;
- depression;
- blood clots;
- pain in the chest/jaw/arm;
- stomach ache;
- changes in the nature of periods
- vision problems (temporary loss of vision, blurred vision);
- slurred speech;
- bad concentration;
- yellowing of the skin;
- swelling of the face/tongue/throat;
- dizziness;
- nervousness;
- rash, itching;
- rapid breathing;
- weakness;
- loss of consciousness;
- pain in the groin;
- unusual/intensified headaches or migraines;
- heavy sweating.
If you have any disturbing side effects after taking the tablets, contact your health care provider immediately.
Contraindications
Do not use Mibelas 24 Fe if you have any of the listed conditions/diseases:
- breast cancer;
- predisposition to breast cancer;
- deficiency of anti-clotting agents;
- gallbladder disease;
- estrogen-dependent tumor;
- a high amount of triglyceride in the blood;
- continuing episodes of swelling;
- recent surgery;
- heart attack;
- coronary artery disease;
- predisposition to blood clotting;
- depression;
- allergies to estrogens or progestins
- migraines;
- retinal thrombosis;
- optic disk edema;
- hypertension;
- lung embolism;
- stroke;
- blood clots;
- predisposition to blood clots;
- liver disorders;
- hypothyroidism;
- low levels of parathyroid hormone;
- smoking;
- cardiovascular problems in the past;
- protein c deficiency.
Interactions
Avoid taking Mibelas 24 Fe if you are already taking any of the following medications:
- ritonavir;
- barbiturates;
- carbamazepine;
- griseofulvin;
- ritonavir;
- exemestane;
- paritaprevir
- phenytoin;
- ospemifene;
- tizanidine;
- tranexamic acid;
- ombitasvir;
- primidone;
- nelfinavir;
- nevirapine;
- rifampin;
- rifabutin;
- tamoxifen;
- St. John’s wort;
- dasabuvir;
- felbamate;
- anastrozole;
- topiramate;
- modafinil.
The contraceptive may affect the results of some laboratory tests (including blood clotting and thyroid).
Before using any new medication, consult your doctor because you may need to use a barrier method of contraception.
Pregnancy and breastfeeding
Use of Mibelas 24 Fe is contraindicated during pregnancy and breastfeeding. Discontinue the treatment if you get pregnant while taking birth control pills. The active components of the contraceptive may penetrate into breast milk and negatively affect the baby. Besides, combination oral contraceptives can slow the production of breast milk and reduce its amount.
What if I miss a pill?
Try not to miss tablets (especially those with hormones) since this increases the risk of pregnancy.
If you missed 1 active tablet in any week:
- take the 2 missed tablets on the day you remember, then take 1 tablet each day per day until you finish the pack;
If you missed 2 tablets in a row in Week 1 or 2:
- take the 2 missed tablets per day for 2 days in a row. Then take 1 tablet each day until your pack is finished. Use an additional non-hormonal method of contraception (for example, condoms) for 7 days;
If you missed 2 tablets in a row in Week 3:
- throw out the rest of the pack and start taking tablets from a new pack the same day is you a First Day starter. If you started your pack on Sunday, keep taking 1 tablet per day until Sunday. On Sunday, discard the rest of the pack and start taking tablets from a new pack. Use an additional non-hormonal method of contraception (for example, condoms) for 7 days;
If you missed 3 tablets in a row in Week 1, 2, or 3:
- throw out the rest of the pack and start taking tablets from a new pack the same day is you a First Day starter. If you started your pack on Sunday, keep taking 1 tablet per day until Sunday. On Sunday, discard the rest of the pack and start taking tablets from a new pack. Use an additional non-hormonal method of contraception (for example, condoms) for 7 days;
Missing 2 or more active tablets increases the risk of not having your period during this month. If you do not have menstrual bleeding for 2 months in a row, contact your healthcare provider because you might be pregnant.
If you missed any of the inactive tablets in Week 4:
- Throw them away and keep taking 1 tablet per day until the pack is empty. Additional methods of contraception are not required.
Precautions
When on the pill, you need to consult a gynecologist every 6 months.
It’s recommended to undergo gynecological and general medical examinations before taking Mibelas 24 Fe for birth control.
Prior to taking the drug, be sure to exclude pregnancy and make sure you do not have any contraindications for use.
If you have gastrointestinal disorders such as severe diarrhea or vomiting, keep taking the medication and use an additional barrier method of birth control for 7 days.
Some women may have spotting when they start taking the tablets (mainly during the first 3 months). In this case, you should keep taking the drug and wait until your body gets used to the hormones. If bleeding continues after 3 months of use or becomes too heavy, contact your health care provider as soon as possible.
Heavy smokers have an increased risk of developing serious cardiovascular side effects. If you are smoking and over the age of 35, choose another method of contraception.
Before using any combination hormonal contraceptives, tell your healthcare provider if you have ever had:
- overweight;
- severe migraines;
- cardiovascular problems;
- high low pressure/low blood pressure;
- lumps, nodules;
- diabetes;
- gallbladder disease;
- irregular menstrual periods;
- liver or kidney disease;
- an abnormal mammogram;
- depression;
- underactive thyroid;
- high cholesterol.
Prior to a scheduled surgery followed by a prolonged bed rest, you should discontinue the treatment for a while. Inform your surgeon that you are using hormonal contraceptives.
Mibelas 24 Fe is not used for the prevention of HIV, AIDS or other sexually transmitted diseases. For this purpose, you must use a condom.
Do not use the tablets after the expiration date.
Keep away from direct sunlight, heat, moisture, out of reach by pets and children.